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Stability and Recovery of DIFICID(®) (Fidaxomicin) 200-mg Crushed Tablet Preparations from Three Delivery Vehicles, and Administration of an Aqueous Dispersion via Nasogastric Tube

Fidaxomicin is approved for the treatment of adults with Clostridium difficile–associated diarrhea, many of whom have difficulty swallowing an intact tablet. The study objective was to evaluate the stability and recovery of crushed DIFICID(®) (fidaxomicin) 200-mg tablets dispersed in water, applesau...

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Detalles Bibliográficos
Autores principales: Tousseeva, Anna, Jackson, J. Derek, Redell, Mark, Henry, Teresa, Hui, Michael, Capurso, Shelley, DeRyke, C. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269826/
https://www.ncbi.nlm.nih.gov/pubmed/25424419
http://dx.doi.org/10.1007/s40268-014-0067-3