CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function

BACKGROUND: It has been suggested that transcriptional upregulation of cerebral artery contractile endothelin (ET(B)) and 5-hydroxytryptamine (5-HT(1B)) receptors play an important role in the development of late cerebral ischemia and increased vasoconstriction after subarachnoid hemorrhage (SAH). W...

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Detalles Bibliográficos
Autores principales: Edvinsson, Lars, Povlsen, Gro Klitgaard, Ahnstedt, Hilda, Waldsee, Roya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269841/
https://www.ncbi.nlm.nih.gov/pubmed/25498987
http://dx.doi.org/10.1186/s12974-014-0207-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269841/
https://www.ncbi.nlm.nih.gov/pubmed/25498987
http://dx.doi.org/10.1186/s12974-014-0207-2

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