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Upregulation of microRNA-196a and microRNA-196b cooperatively correlate with aggressive progression and unfavorable prognosis in patients with colorectal cancer

BACKGROUND: Both microRNA (miR)-196a and miR-196b are implicated in normal cell differentiation, proliferation, and in tumorigenesis of various cancer types. Especially, miR-196a exerts a pro-oncogenic influence in colorectal cancer (CRC) cells and miR-196b expression is upregulated in CRC tissues....

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Detalles Bibliográficos
Autores principales: Ge, Jie, Chen, Zihua, Li, Ruixing, Lu, Tailiang, Xiao, Guangfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269845/
https://www.ncbi.nlm.nih.gov/pubmed/25525411
http://dx.doi.org/10.1186/s12935-014-0128-2