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The microRNA miR-29a is associated with human immunodeficiency virus latency

BACKGROUND: Latent reservoirs of HIV-1 provide a major challenge to its cure. There are increasing reports of interplay between HIV-1 replication and host miRNAs. Several host miRNAs, which potentially target the nef-3′LTR region of HIV-1 RNA, including miR-29a, are proposed to promote latency. FIND...

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Detalles Bibliográficos
Autores principales: Patel, Paresh, Ansari, Mohammad Yunus, Bapat, Shraddha, Thakar, Madhuri, Gangakhedkar, Raman, Jameel, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269869/
https://www.ncbi.nlm.nih.gov/pubmed/25486977
http://dx.doi.org/10.1186/s12977-014-0108-6