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Anesthetic Diffusion Through Lipid Membranes Depends on the Protonation Rate
Hundreds of substances possess anesthetic action. However, despite decades of research and tests, a golden rule is required to reconcile the diverse hypothesis behind anesthesia. What makes an anesthetic to be local or general in the first place? The specific targets on proteins, the solubility in l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269894/ https://www.ncbi.nlm.nih.gov/pubmed/25520016 http://dx.doi.org/10.1038/srep07534 |