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Could high-concentration rifampicin kill rifampicin-resistant M. tuberculosis? Rifampicin MIC test in rifampicin-resistant isolates from patients with osteoarticular tuberculosis

PURPOSE: Several studies have shown that the intralesional concentration of rifampicin in osteoarticular tuberculosis is typically at a subtherapeutic level. Sustained or controlled release by novel drug delivery systems has been investigated to maintain an effective rifampicin concentration, but th...

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Detalles Bibliográficos
Autores principales: Zhang, Zehua, Dai, Fei, Luo, Fei, Zhong, Min, Huang, Zhenggu, Hou, Tianyong, Xu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269955/
https://www.ncbi.nlm.nih.gov/pubmed/25467069
http://dx.doi.org/10.1186/s13018-014-0124-1