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Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice

BACKGROUND: We investigated the effects of mycophenolate mofetil (MMF) on kidney function and on protein phosphorylation in a mouse model for the human Alport syndrome. METHODS: COL4A3-deficient (COL4A3−/−) mice were randomly allocated to receive a placebo (PLC COL4A3−/−) or MMF treatment (MMF COL4A...

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Detalles Bibliográficos
Autores principales: Petrova, Darinka Todorova, Schultze, Frank Christian, Brandhorst, Gunnar, Luchs, Klaus-Dieter, Lenz, Christof, Urlaub, Henning, Rubel, Diana, Gross, Oliver, Walson, Philip D, Oellerich, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269973/
https://www.ncbi.nlm.nih.gov/pubmed/25525413
http://dx.doi.org/10.1186/s12953-014-0056-z