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Mycophenolic acid AUC in Thai kidney transplant recipients receiving low dose mycophenolate and its association with UGT2B7 polymorphisms

BACKGROUND: Despite use of a lower mycophenolate dose in Thai kidney transplant patients, acceptable graft and patient outcomes can be achieved. We therefore examined the pharmacokinetics of mycophenolic acid (MPA) by area under the curve (AUC) and investigated genetic contribution in mycophenolate...

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Detalles Bibliográficos
Autores principales: Pithukpakorn, Manop, Tiwawanwong, Tiwat, Lalerd, Yupaporn, Assawamakin, Anunchai, Premasathian, Nalinee, Tasanarong, Adis, Thongnoppakhun, Wanna, Vongwiwatana, Attapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270037/
https://www.ncbi.nlm.nih.gov/pubmed/25540593
http://dx.doi.org/10.2147/PGPM.S72760