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Increased Wnt5a mRNA Expression in Advanced Atherosclerotic Lesions, and Oxidized LDL Treated Human Monocyte-Derived Macrophages

OBJECTIVE: Wnt5a is a secreted glycoprotein highly present in atherosclerotic lesions. Uptake of oxidized-low density lipoprotein (ox-LDL) by monocytes/macrophages plays a critical role in atherosclerosis. The objective of this study was to determine if Wnt5a mRNA expression correlates with the seve...

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Detalles Bibliográficos
Autores principales: Bhatt, Pooja M., Lewis, Christopher J., House, Denise L., Keller, Chad M., Kohn, Leonard D., Silver, Mitchell J., McCall, Kelly D., Goetz, Douglas J., Malgor, Ramiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270053/
https://www.ncbi.nlm.nih.gov/pubmed/25530821