Cargando…

Nanodomain coupling explains Ca(2+) independence of transmitter release time course at a fast central synapse

A puzzling property of synaptic transmission, originally established at the neuromuscular junction, is that the time course of transmitter release is independent of the extracellular Ca(2+) concentration ([Ca(2+)](o)), whereas the rate of release is highly [Ca(2+)](o)-dependent. Here, we examine the...

Descripción completa

Detalles Bibliográficos
Autores principales: Arai, Itaru, Jonas, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270082/
https://www.ncbi.nlm.nih.gov/pubmed/25487988
http://dx.doi.org/10.7554/eLife.04057