Methamphetamine-induced short-term increase and long-term decrease in spatial working memory affects protein Kinase M zeta (PKMζ), dopamine, and glutamate receptors

Methamphetamine (MA) is a toxic, addictive drug shown to modulate learning and memory, yet the neural mechanisms are not fully understood. We investigated the effects of 2 weekly injections of MA (30 mg/kg) on working memory using the radial 8-arm maze (RAM) across 5 weeks in adolescent-age mice. MA...

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Detalles Bibliográficos
Autores principales: Braren, Stephen H., Drapala, Damian, Tulloch, Ingrid K., Serrano, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270177/
https://www.ncbi.nlm.nih.gov/pubmed/25566006
http://dx.doi.org/10.3389/fnbeh.2014.00438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270177/
https://www.ncbi.nlm.nih.gov/pubmed/25566006
http://dx.doi.org/10.3389/fnbeh.2014.00438

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