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Mitochondria dysfunction in lung cancer-induced muscle wasting in C2C12 myotubes

Aims: Cancer cachexia is a syndrome which results in severe loss of muscle mass and marked fatigue. Conditioned media from cachexia-inducing cancer cells triggers metabolic dysfunction in skeletal muscle, including decreased mitochondrial respiration, which may contribute to fatigue. We hypothesized...

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Detalles Bibliográficos
Autores principales: McLean, Julie B., Moylan, Jennifer S., Andrade, Francisco H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270181/
https://www.ncbi.nlm.nih.gov/pubmed/25566096
http://dx.doi.org/10.3389/fphys.2014.00503