Cargando…

Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates

Depression is a complex, heterogeneous mental disorder. Currently available antidepressants are only effective in about one-third to one-half of all patients. The mechanisms underlying antidepressant response and treatment resistance are poorly understood. Recent clinical evidence implicates the inv...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, M, Lu, X-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270309/
https://www.ncbi.nlm.nih.gov/pubmed/25463972
http://dx.doi.org/10.1038/tp.2014.126