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Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates
Depression is a complex, heterogeneous mental disorder. Currently available antidepressants are only effective in about one-third to one-half of all patients. The mechanisms underlying antidepressant response and treatment resistance are poorly understood. Recent clinical evidence implicates the inv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270309/ https://www.ncbi.nlm.nih.gov/pubmed/25463972 http://dx.doi.org/10.1038/tp.2014.126 |