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Impact of losartan and angiotensin II on the expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rat vascular smooth muscle cells

The present study aimed to investigate the impact of losartan and angiotensin II (AngII) on the expression of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1), secreted by rat vascular smooth muscle cells (VSMCs). Rat VSMCs were isolated and cultured in differe...

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Detalles Bibliográficos
Autores principales: GUO, YAN-SONG, WU, ZONG-GUI, YANG, JUN-KE, CHEN, XIN-JING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270314/
https://www.ncbi.nlm.nih.gov/pubmed/25405958
http://dx.doi.org/10.3892/mmr.2014.2952