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Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein

The aim of the present study was to examine the effects of proteasome inhibitor (PI)-induced autophagy on PC12 cells overexpressing A53T mutant α-synuclein (α-syn) by detecting alterations in the levels of microtubule-associated protein 1A/1B light chain (LC3)(+) autophagosomes and the lysotracker-p...

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Detalles Bibliográficos
Autores principales: LAN, DANMEI, WANG, WENZHAO, ZHUANG, JIANHUA, ZHAO, ZHONGXIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270325/
https://www.ncbi.nlm.nih.gov/pubmed/25434876
http://dx.doi.org/10.3892/mmr.2014.3011