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Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics

[Image: see text] UDP-galactopyranose mutase (UGM) catalyzes the interconversion between UDP-galactopyranose and UDP-galactofuranose. Absent in humans, galactofuranose is found in bacterial and fungal cell walls and is a cell surface virulence factor in protozoan parasites. For these reasons, UGMs a...

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Detalles Bibliográficos
Autores principales: Da Fonseca, Isabel, Qureshi, Insaf A., Mehra-Chaudhary, Ritcha, Kizjakina, Karina, Tanner, John J., Sobrado, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270374/
https://www.ncbi.nlm.nih.gov/pubmed/25412209
http://dx.doi.org/10.1021/bi501008z