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Adsorption-Induced Changes in Ribonuclease A Structure and Enzymatic Activity on Solid Surfaces

[Image: see text] Ribonuclease A (RNase A) is a small globular enzyme that lyses RNA. The remarkable solution stability of its structure and enzymatic activity has led to its investigation to develop a new class of drugs for cancer chemotherapeutics. However, the successful clinical application of R...

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Detalles Bibliográficos
Autores principales: Wei, Yang, Thyparambil, Aby A., Wu, Yonnie, Latour, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270395/
https://www.ncbi.nlm.nih.gov/pubmed/25420087
http://dx.doi.org/10.1021/la503854a