Metadynamics Simulations Reveal a Na(+) Independent Exiting Path of Galactose for the Inward-Facing Conformation of vSGLT

Sodium-Galactose Transporter (SGLT) is a secondary active symporter which accumulates sugars into cells by using the electrochemical gradient of Na(+) across the membrane. Previous computational studies provided insights into the release process of the two ligands (galactose and sodium ion) into the...

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Detalles Bibliográficos
Autores principales: Bisha, Ina, Rodriguez, Alex, Laio, Alessandro, Magistrato, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270436/
https://www.ncbi.nlm.nih.gov/pubmed/25522004
http://dx.doi.org/10.1371/journal.pcbi.1004017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270436/
https://www.ncbi.nlm.nih.gov/pubmed/25522004
http://dx.doi.org/10.1371/journal.pcbi.1004017

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