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Metadynamics Simulations Reveal a Na(+) Independent Exiting Path of Galactose for the Inward-Facing Conformation of vSGLT
Sodium-Galactose Transporter (SGLT) is a secondary active symporter which accumulates sugars into cells by using the electrochemical gradient of Na(+) across the membrane. Previous computational studies provided insights into the release process of the two ligands (galactose and sodium ion) into the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270436/ https://www.ncbi.nlm.nih.gov/pubmed/25522004 http://dx.doi.org/10.1371/journal.pcbi.1004017 |