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Dietary (−)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing()

Flavonoids, a group of dietary polyphenols have been shown to possess cognitive health benefits. Epidemiologic evidence suggests that they could play a role in risk reduction in dementia. Amyloid precursor protein processing and the subsequent generation of amyloid beta (Aβ) are central to the patho...

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Detalles Bibliográficos
Autores principales: Cox, Carla J., Choudhry, Fahd, Peacey, Eleanor, Perkinton, Michael S., Richardson, Jill C., Howlett, David R., Lichtenthaler, Stefan F., Francis, Paul T., Williams, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270442/
https://www.ncbi.nlm.nih.gov/pubmed/25316600
http://dx.doi.org/10.1016/j.neurobiolaging.2014.07.032