Cargando…

Synthesis of aminoacylated N(6),N(6)-dimethyladenosine solid support for efficient access to hydrolysis-resistant 3′-charged tRNA mimics

RNA-amino acid and RNA-peptide conjugates that mimic charged tRNA 3′-ends are valuable substrates for structural and functional investigations of ribosomal complexes. To obtain such conjugates, most synthetic approaches that are found in the literature make use of puromycin. This well available amin...

Descripción completa

Detalles Bibliográficos
Autores principales: Neuner, Sandro, Micura, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270447/
https://www.ncbi.nlm.nih.gov/pubmed/25457127
http://dx.doi.org/10.1016/j.bmc.2014.09.054