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Mucolipin Co-deficiency Causes Accelerated Endolysosomal Vacuolation of Enterocytes and Failure-to-Thrive from Birth to Weaning

During the suckling period, intestinal enterocytes are richly endowed with endosomes and lysosomes, which they presumably utilize for the uptake and intracellular digestion of milk proteins. By weaning, mature intestinal enterocytes replace those rich in lysosomes. We found that mouse enterocytes be...

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Detalles Bibliográficos
Autores principales: Remis, Natalie N., Wiwatpanit, Teerawat, Castiglioni, Andrew J., Flores, Emma N., Cantú, Jorge A., García-Añoveros, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270466/
https://www.ncbi.nlm.nih.gov/pubmed/25521295
http://dx.doi.org/10.1371/journal.pgen.1004833