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Mucolipin Co-deficiency Causes Accelerated Endolysosomal Vacuolation of Enterocytes and Failure-to-Thrive from Birth to Weaning
During the suckling period, intestinal enterocytes are richly endowed with endosomes and lysosomes, which they presumably utilize for the uptake and intracellular digestion of milk proteins. By weaning, mature intestinal enterocytes replace those rich in lysosomes. We found that mouse enterocytes be...
Autores principales: | Remis, Natalie N., Wiwatpanit, Teerawat, Castiglioni, Andrew J., Flores, Emma N., Cantú, Jorge A., García-Añoveros, Jaime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270466/ https://www.ncbi.nlm.nih.gov/pubmed/25521295 http://dx.doi.org/10.1371/journal.pgen.1004833 |
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