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Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation

Erythropoiesis is one of the best understood examples of cellular differentiation. Morphologically, erythroid differentiation proceeds in a nearly identical fashion between humans and mice, but recent evidence has shown that networks of gene expression governing this process are divergent between sp...

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Detalles Bibliográficos
Autores principales: Ulirsch, Jacob C., Lacy, Jessica N., An, Xiuli, Mohandas, Narla, Mikkelsen, Tarjei S., Sankaran, Vijay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270484/
https://www.ncbi.nlm.nih.gov/pubmed/25521328
http://dx.doi.org/10.1371/journal.pgen.1004890