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Syd/JIP3 and JNK Signaling Are Required for Myonuclear Positioning and Muscle Function

Highlighting the importance of proper intracellular organization, many muscle diseases are characterized by mispositioned myonuclei. Proper positioning of myonuclei is dependent upon the microtubule motor proteins, Kinesin-1 and cytoplasmic Dynein, and there are at least two distinct mechanisms by w...

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Detalles Bibliográficos
Autores principales: Schulman, Victoria K., Folker, Eric S., Rosen, Jonathan N., Baylies, Mary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270490/
https://www.ncbi.nlm.nih.gov/pubmed/25522254
http://dx.doi.org/10.1371/journal.pgen.1004880