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Refinement of the MHC Risk Map in a Scandinavian Primary Sclerosing Cholangitis Population

BACKGROUND: Genetic variants within the major histocompatibility complex (MHC) represent the strongest genetic susceptibility factors for primary sclerosing cholangitis (PSC). Identifying the causal variants within this genetic complex represents a major challenge due to strong linkage disequilibriu...

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Detalles Bibliográficos
Autores principales: Næss, Sigrid, Lie, Benedicte A., Melum, Espen, Olsson, Marita, Hov, Johannes R., Croucher, Peter J. P., Hampe, Jochen, Thorsby, Erik, Bergquist, Annika, Traherne, James A., Schrumpf, Erik, Boberg, Kirsten Muri, Schreiber, Stefan, Franke, Andre, Karlsen, Tom H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270690/
https://www.ncbi.nlm.nih.gov/pubmed/25521205
http://dx.doi.org/10.1371/journal.pone.0114486