Characterization of the Ca(2+)-Gated and Voltage-Dependent K(+)-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics. The mode of action of cyclooctadepsipeptides is only partially understood, but involves the latrophilin Lat-1 receptor and...

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Detalles Bibliográficos
Autores principales: Kulke, Daniel, von Samson-Himmelstjerna, Georg, Miltsch, Sandra M., Wolstenholme, Adrian J., Jex, Aaron R., Gasser, Robin B., Ballesteros, Cristina, Geary, Timothy G., Keiser, Jennifer, Townson, Simon, Harder, Achim, Krücken, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270693/
https://www.ncbi.nlm.nih.gov/pubmed/25521608
http://dx.doi.org/10.1371/journal.pntd.0003401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270693/
https://www.ncbi.nlm.nih.gov/pubmed/25521608
http://dx.doi.org/10.1371/journal.pntd.0003401

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