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Characterization of the Ca(2+)-Gated and Voltage-Dependent K(+)-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics. The mode of action of cyclooctadepsipeptides is only partially understood, but involves the latrophilin Lat-1 receptor and...

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Detalles Bibliográficos
Autores principales:	Kulke, Daniel, von Samson-Himmelstjerna, Georg, Miltsch, Sandra M., Wolstenholme, Adrian J., Jex, Aaron R., Gasser, Robin B., Ballesteros, Cristina, Geary, Timothy G., Keiser, Jennifer, Townson, Simon, Harder, Achim, Krücken, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270693/ https://www.ncbi.nlm.nih.gov/pubmed/25521608 http://dx.doi.org/10.1371/journal.pntd.0003401

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