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A Phase Ia Study to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 CS Administered Alone and with MVA CS

BACKGROUND: Plasmodium falciparum (P. falciparum) malaria remains a significant cause of mortality and morbidity throughout the world. Development of an effective vaccine would be a key intervention to reduce the considerable social and economic impact of malaria. METHODOLOGY: We conducted a Phase I...

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Detalles Bibliográficos
Autores principales: de Barra, Eoghan, Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Hennigan, Kerrie, Collins, Ann, Berrie, Eleanor, Lawrie, Alison M., Gilbert, Sarah C., Nicosia, Alfredo, McConkey, Samuel J., Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270740/
https://www.ncbi.nlm.nih.gov/pubmed/25522180
http://dx.doi.org/10.1371/journal.pone.0115161