Membrane Morphology Is Actively Transformed by Covalent Binding of the Protein Atg8 to PE-Lipids

Autophagy is a cellular degradation pathway involving the shape transformation of lipid bilayers. During the onset of autophagy, the water-soluble protein Atg8 binds covalently to phosphatdylethanolamines (PEs) in the membrane in an ubiquitin-like reaction coupled to ATP hydrolysis. We reconstituted...

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Detalles Bibliográficos
Autores principales: Knorr, Roland L., Nakatogawa, Hitoshi, Ohsumi, Yoshinori, Lipowsky, Reinhard, Baumgart, Tobias, Dimova, Rumiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270758/
https://www.ncbi.nlm.nih.gov/pubmed/25522362
http://dx.doi.org/10.1371/journal.pone.0115357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270758/
https://www.ncbi.nlm.nih.gov/pubmed/25522362
http://dx.doi.org/10.1371/journal.pone.0115357

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