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Ginsenoside Rg3 Inhibits Melanoma Cell Proliferation through Down-Regulation of Histone Deacetylase 3 (HDAC3) and Increase of p53 Acetylation

Malignant melanoma is an aggressive and deadly form of skin cancer, and despite recent advances in available therapies, is still lacking in completely effective treatments. Rg3, a monomer extracted from ginseng roots, has been attempted for the treatment of many cancers. It is reported that the expr...

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Detalles Bibliográficos
Autores principales: Shan, Xiu, Fu, Yuan-Shan, Aziz, Faisal, Wang, Xiao-Qi, Yan, Qiu, Liu, Ji-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270766/
https://www.ncbi.nlm.nih.gov/pubmed/25521755
http://dx.doi.org/10.1371/journal.pone.0115401