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HSV-2-Driven Increase in the Expression of α(4)β(7) Correlates with Increased Susceptibility to Vaginal SHIV(SF162P3) Infection

The availability of highly susceptible HIV target cells that can rapidly reach the mucosal lymphoid tissues may increase the chances of an otherwise rare transmission event to occur. Expression of α(4)β(7) is required for trafficking of immune cells to gut inductive sites where HIV can expand and it...

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Detalles Bibliográficos
Autores principales: Goode, Diana, Truong, Rosaline, Villegas, Guillermo, Calenda, Giulia, Guerra-Perez, Natalia, Piatak, Michael, Lifson, Jeffrey D., Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa, Martinelli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270786/
https://www.ncbi.nlm.nih.gov/pubmed/25521298
http://dx.doi.org/10.1371/journal.ppat.1004567