Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivo

Carcinoids are slow-growing neuroendocrine tumors (NETs) that are characterized by hormone overproduction; surgery is currently the only option for treatment. Activation of the Notch pathway has previously been shown to have a role in tumor suppression in NETs. The marine-derived thiodepsipeptide th...

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Detalles Bibliográficos
Autores principales: Wyche, Thomas P., Dammalapati, Ajitha, Cho, Hyunah, Harrison, April D., Kwon, Glen S., Chen, Herbert, Bugni, Tim S., Jaskula-Sztul, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270822/
https://www.ncbi.nlm.nih.gov/pubmed/25412645
http://dx.doi.org/10.1038/cgt.2014.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270822/
https://www.ncbi.nlm.nih.gov/pubmed/25412645
http://dx.doi.org/10.1038/cgt.2014.57

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