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Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivo
Carcinoids are slow-growing neuroendocrine tumors (NETs) that are characterized by hormone overproduction; surgery is currently the only option for treatment. Activation of the Notch pathway has previously been shown to have a role in tumor suppression in NETs. The marine-derived thiodepsipeptide th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270822/ https://www.ncbi.nlm.nih.gov/pubmed/25412645 http://dx.doi.org/10.1038/cgt.2014.57 |