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Modeling human development and disease in pluripotent stem cell-derived gastric organoids

Gastric diseases, including peptic ulcer disease and gastric cancer, affect 10% of the world’s population and are largely due to chronic H. pylori infection(1–3). Species differences in embryonic development and architecture of the adult stomach make animal models suboptimal for studying human stoma...

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Detalles Bibliográficos
Autores principales: McCracken, Kyle W., Catá, Emily M., Crawford, Calyn M., Sinagoga, Katie L., Schumacher, Michael, Rockich, Briana E., Tsai, Yu-Hwai, Mayhew, Christopher N., Spence, Jason R., Zavros, Yana, Wells, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270898/
https://www.ncbi.nlm.nih.gov/pubmed/25363776
http://dx.doi.org/10.1038/nature13863