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Modeling human development and disease in pluripotent stem cell-derived gastric organoids
Gastric diseases, including peptic ulcer disease and gastric cancer, affect 10% of the world’s population and are largely due to chronic H. pylori infection(1–3). Species differences in embryonic development and architecture of the adult stomach make animal models suboptimal for studying human stoma...
Autores principales: | McCracken, Kyle W., Catá, Emily M., Crawford, Calyn M., Sinagoga, Katie L., Schumacher, Michael, Rockich, Briana E., Tsai, Yu-Hwai, Mayhew, Christopher N., Spence, Jason R., Zavros, Yana, Wells, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270898/ https://www.ncbi.nlm.nih.gov/pubmed/25363776 http://dx.doi.org/10.1038/nature13863 |
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