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GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors
A fundamental challenge in treating disease is identifying molecular states that affect cellular responses to drugs. Here, we focus on GSK-3, a key regulator for many of the hallmark behaviors of cancer cells. We alter GSK-3 activity in colon epithelial cells to test its role in modulating drug resp...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270937/ https://www.ncbi.nlm.nih.gov/pubmed/25402767 http://dx.doi.org/10.1038/nchembio.1690 |