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Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

Metazoans identify and eliminate bacterial pathogens in microbe-rich environments such as the intestinal lumen, however the mechanisms are unclear. Potentially, host cells employ intracellular surveillance or stress response programs to detect pathogens that target monitored cellular activities to i...

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Detalles Bibliográficos
Autores principales: Pellegrino, Mark W., Nargund, Amrita M., Kirienko, Natalia V., Gillis, Reba, Fiorese, Christopher J., Haynes, Cole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270954/
https://www.ncbi.nlm.nih.gov/pubmed/25274306
http://dx.doi.org/10.1038/nature13818