Cargando…
Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
Metazoans identify and eliminate bacterial pathogens in microbe-rich environments such as the intestinal lumen, however the mechanisms are unclear. Potentially, host cells employ intracellular surveillance or stress response programs to detect pathogens that target monitored cellular activities to i...
Autores principales: | Pellegrino, Mark W., Nargund, Amrita M., Kirienko, Natalia V., Gillis, Reba, Fiorese, Christopher J., Haynes, Cole M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270954/ https://www.ncbi.nlm.nih.gov/pubmed/25274306 http://dx.doi.org/10.1038/nature13818 |
Ejemplares similares
-
Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial UPR
por: Lin, Yi-Fan, et al.
Publicado: (2016) -
UPR(mt) regulation and output: a stress response mediated by mitochondrial-nuclear communication
por: Melber, Andrew, et al.
Publicado: (2018) -
SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension
por: Gao, Kaiyu, et al.
Publicado: (2019) -
Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
por: Baker, Brooke M., et al.
Publicado: (2012) -
Box C/D small nucleolar ribonucleoproteins regulate mitochondrial surveillance and innate immunity
por: Tjahjono, Elissa, et al.
Publicado: (2022)