High mobility group box 1 is a novel deacetylation target of Sirtuin1

High mobility group box 1 (HMGB1) undergoes acetylation, nuclear-to-cytoplasmic translocation and release from stressed kidneys, unleashing a signaling cascade of events leading to systemic inflammation. Here we tested whether the deacetylase activity of Sirtuin1 (SIRT1) participates in regulating n...

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Detalles Bibliográficos
Autores principales: Rabadi, May M., Xavier, Sandhya, Vasko, Radovan, Kaur, Kavneet, Goligorksy, Michael S., Ratliff, Brian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270955/
https://www.ncbi.nlm.nih.gov/pubmed/24940804
http://dx.doi.org/10.1038/ki.2014.217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270955/
https://www.ncbi.nlm.nih.gov/pubmed/24940804
http://dx.doi.org/10.1038/ki.2014.217

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