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Spinal release of tumour necrosis factor activates c-Jun N-terminal kinase and mediates inflammation-induced hypersensitivity

BACKGROUND: Mounting evidence points to individual contributions of tumour necrosis factor-alpha (TNF) and the c-Jun N-terminal kinase (JNK) pathway to the induction and maintenance of various pain states. Here we explore the role of spinal TNF and JNK in carrageenan-induced hypersensitivity. As lin...

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Detalles Bibliográficos
Autores principales:	Bas, DB, Abdelmoaty, S, Sandor, K, Codeluppi, S, Fitzsimmons, B, Steinauer, J, Hua, XY, Yaksh, TL, Svensson, CI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270961/ https://www.ncbi.nlm.nih.gov/pubmed/24942612 http://dx.doi.org/10.1002/ejp.544

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