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Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter

Peptide transport plays an important role in cellular homeostasis as a key route for nitrogen acquisition in mammalian cells. PepT1 and PepT2, the mammalian proton coupled peptide transporters (POTs), function to assimilate and retain diet-derived peptides and play important roles in drug pharmacoki...

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Detalles Bibliográficos
Autores principales: Parker, Joanne L, Mindell, Joseph A, Newstead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271188/
https://www.ncbi.nlm.nih.gov/pubmed/25457052
http://dx.doi.org/10.7554/eLife.04273