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A HIERARCHY OF ANKYRIN/SPECTRIN COMPLEXES CLUSTERS SODIUM CHANNELS AT NODES OF RANVIER

The scaffolding protein ankyrinG is required for Na+ channel clustering at axon initial segments. It is also considered essential for Na+ channel clustering at nodes of Ranvier to facilitate fast and efficient action potential propagation. However, in contrast to these widely accepted roles, we show...

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Detalles Bibliográficos
Autores principales: Ho, Tammy Szu-Yu, Zollinger, Daniel R., Chang, Kae-Jiun, Xu, Mingxuan, Cooper, Edward C., Stankewich, Michael C., Bennett, Vann, Rasband, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271271/
https://www.ncbi.nlm.nih.gov/pubmed/25362473
http://dx.doi.org/10.1038/nn.3859