FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling

Hematopoietic stem cells (HSCs) derive from hemogenic endothelial cells of the primitive dorsal aorta (DA) during vertebrate embryogenesis. The molecular mechanisms governing this unique endothelial to hematopoietic transition remain unclear. Here, we demonstrate a novel requirement for fibroblast g...

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Detalles Bibliográficos
Autores principales: Lee, Yoonsung, Manegold, Jennifer E, Kim, Albert D, Pouget, Claire, Stachura, David L, Clements, Wilson K, Traver, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271318/
https://www.ncbi.nlm.nih.gov/pubmed/25428693
http://dx.doi.org/10.1038/ncomms6583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271318/
https://www.ncbi.nlm.nih.gov/pubmed/25428693
http://dx.doi.org/10.1038/ncomms6583

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