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How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest

Vpr is one of the most enigmatic viral auxiliary proteins of HIV. During the past twenty years, several activities have been ascribed to this viral protein, but one, its ability to mediate cell cycle arrest at the G2 to M transition has been the most extensively studied. Nonetheless, the genuine rol...

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Detalles Bibliográficos
Autores principales: Blondot, Marie-Lise, Dragin, Loic, Lahouassa, Hichem, Margottin-Goguet, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271344/
https://www.ncbi.nlm.nih.gov/pubmed/25496524
http://dx.doi.org/10.1186/s12977-014-0117-5