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Added predictive value of omics data: specific issues related to validation illustrated by two case studies

BACKGROUND: In the last years, the importance of independent validation of the prediction ability of a new gene signature has been largely recognized. Recently, with the development of gene signatures which integrate rather than replace the clinical predictors in the prediction rule, the focus has b...

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Detalles Bibliográficos
Autores principales: Bin, Riccardo De, Herold, Tobias, Boulesteix, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271356/
https://www.ncbi.nlm.nih.gov/pubmed/25352096
http://dx.doi.org/10.1186/1471-2288-14-117