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Added predictive value of omics data: specific issues related to validation illustrated by two case studies
BACKGROUND: In the last years, the importance of independent validation of the prediction ability of a new gene signature has been largely recognized. Recently, with the development of gene signatures which integrate rather than replace the clinical predictors in the prediction rule, the focus has b...
Autores principales: | Bin, Riccardo De, Herold, Tobias, Boulesteix, Anne-Laure |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271356/ https://www.ncbi.nlm.nih.gov/pubmed/25352096 http://dx.doi.org/10.1186/1471-2288-14-117 |
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