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Increased Th17 cells in flow cytometer-sorted CD45RO-positive memory CD4 T cells from patients with systemic lupus erythematosus

OBJECTIVES: Th17/IL-17 dysregulation is involved in human autoimmunity, and recent evidence suggests the character of long-lived differentiated memory cells in Th17. By directly measuring the peripheral blood mononuclear cells (PBMC), elevated circulating frequencies of Th17 cells have been reported...

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Detalles Bibliográficos
Autores principales: Liu, Ming-Fei, Wang, Chrong-Reen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271411/
https://www.ncbi.nlm.nih.gov/pubmed/25553252
http://dx.doi.org/10.1136/lupus-2014-000062