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Risk-reducing salpingo-oophorectomy: a meta-analysis on impact on ovarian cancer risk and all cause mortality in BRCA 1 and BRCA 2 mutation carriers

BACKGROUND: Women with BRCA1 and BRCA2 mutation carriers are at substantially elevated risk of developing ovarian cancer. The aim of the meta-analysis is to clarify the role of risk-reducing salpingo-oophorectomy (RRSO) to reduce ovarian cancer risk and mortality in women with BRCA 1 and BRCA 2 muta...

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Detalles Bibliográficos
Autores principales: Marchetti, Claudia, De Felice, Francesca, Palaia, Innocenza, Perniola, Giorgia, Musella, Angela, Musio, Daniela, Muzii, Ludovico, Tombolini, Vincenzo, Panici, Pierluigi Benedetti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271468/
https://www.ncbi.nlm.nih.gov/pubmed/25494812
http://dx.doi.org/10.1186/s12905-014-0150-5